Professor :
Hidekazu Hiroaki, PhD.
Associate Professor :
Tetsuya Kodama, PhD.
In order to understand the mechanism(s) of action of drugs and proteins, their three-dimensional structures and intermolecular interactions should be quantitatively evaluated. In turn, such studies can enable the rapid and rational design of novel drugs. This laboratory implements research and education in molecular pharmacology based on the three-dimensional structure of drugs, proteins and nucleic acids, following the process from structural biology to drug development with special consideration for new generation drugs (e.g., antibodies and nucleic acids). With respect to methodologies, we primarily use nuclear magnetic resonance (high field NMR) in combination with X-ray crystallography.
